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10.1016/j.tiv.2007.01.008

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reported that treatments with ARB and IGF-1 enhanced Trolox-equivalent antioxidant capacity and increased levels of antioxidant enzymes (Tanaka et al., 2024)

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Prolonged use of Vitamin B6 (over 2 months) at high doses exceeding 1g/day can lead to severe peripheral neuropathy, with symptoms including unsteady gait and numbness in the hands and feet